Hashimoto encephalopathy

Introduction
There continues to be debate as to whether this condition actually exists, or whether reported cases represent patients with other types of autoimmune encephalitis who happened to have positive thyroid-associated antibodies.

Anti-thyroid peroxidase antibodies
One study suggested very poor disease-specificity, as these antibodies have similar frequencies in patients with suspected encephalitis compared with controls.

Anti-NH2-α-enolase antibodies
One study suggested very poor disease-specificity, as these antibodies have similar frequencies in patients with suspected encephalitis compared with controls.